POTENTIAL OF SNAKEHEAD FISH (OPHIOCEPHALUS STRIATUS) IN ACCELERATING WOUND HEALING

  • Robert Tungadi Department of Pharmacy, Faculty of Sport and Health, State University of Gorontalo, Gorontalo, Indonesia

Abstract

Snakehead fish (Ophiocephalus striatus) (SF) is a type of fish that lives in fresh water and is widely known by the public. The properties and uses of SF have been scientifically proven to increase albumin levels and immune system as well as speed up the process of post-operative wound healing. The nutritional content of SF consists of albumin protein, amino acids, unsaturated fatty acids and minerals. Bioactive compounds that play a role in accelerating the wound healing process are albumin, glycine, and zinc (Zn). Wound healing is very dependent on the biochemical processes that occur on the skin involving intrinsic and extrinsic factors. This healing process will be accelerated with the help of dried SF extract which is designed in topical form such as cream or gel. Among albumin, glycine and Zn are important for wound healing because this protein is able to bind Zn and carry it in blood plasma. Zn deficiency reduces the wound healing process. Because of this nutrient, and other vitamins, it is present in SF extract so that it can trigger the formation of Endothelial Progenitor Cells (EPC) and accelerate wound healing. The presence of Zn in SF extract is likely to be a key factor playing a role in wound healing and also increases the appetite of children. Zn is an important mineral in the structure and function of cell membranes. Zn supplementation can limit membrane damage which is caused by free radicals during inflammation. Furthermore, Zn is also involved in the immune system, from the defense system by the skin to the regulation of genes in lymphocytes.


                         rw23.gif


Google_scholar_image10.JPG  PubMed1.jpg


Peer Review History:


Received 15 September 2019;   Revised 1 November; Accepted 6 November, Available online 15 November 2019


Academic Editor: Dr. DANIYAN Oluwatoyin Michaelorcid22.jpg, Obafemi Awolowo University, ILE-IFE, Nigeria, toyinpharm@gmail.com


UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.


Received file:blue_23983.gif                Reviewer's Comments:download_logo_r_29189.gif


Average Peer review marks at initial stage: 6.0/10


Average Peer review marks at publication stage: 7.5/10


Reviewer(s) detail:


Asmaa Ahmed Mohamed Ahmed Khalifaorcid22.jpg, Pharos University, Alexandria, Egypt, asmaa.khalifa@pua.edu.eg


Dr. Marwa A. A. Fayedorcid22.jpg, University of Sadat City, Egypt, maafayed@gmail.com


 Similar Articles:


WOUND HEALING ACTIVITY OF JATROPHA TANJORENSIS LEAVES


WOUND DRESSINGS UPLOADED WITH MYRTLE BERRIES EXTRACT AND NIGELLA SATIVA HONEY


Article is cited by:


Robert Tungadi, Teti Sutriyati Tuloli, Widysusanti Abdulkadir , Nurain Thomas , Madania Madania , Ani Mustapa Hasan , Zulfiayu Sapiun. COVID-19: Clinical Characteristics and Molecular Levels of Candidate Compounds of Prospective Herbal and Modern Drugs in Indonesia. Pharm Sci. 2020;26(Suppl 1): S12-S23. PubMed

Keywords: Albumin, glycine, snakehead fish, wound, zinc

Downloads

Download data is not yet available.
Comments

Statistics
240 Views | 328 Downloads
How to Cite
Tungadi, R. “POTENTIAL OF SNAKEHEAD FISH (OPHIOCEPHALUS STRIATUS) IN ACCELERATING WOUND HEALING”. Universal Journal of Pharmaceutical Research, Vol. 4, no. 5, Nov. 2019, doi:https://doi.org/10.22270/ujpr.v4i5.316.
Section
Review Articles