EFFECT OF DIETARY FACTORS AND NUTRITIONAL STATUS ON SERUM CALCIUM AND PHOSPHORUS LEVELS IN CKD PATIENTS ON TREATMENT IN A TERTIARY CARE SETTING IN NORTH INDIA
Objective: The control of phosphorus and calcium metabolism is one of the objectives in treatment protocol for CKD patients. The levels of these minerals in serum are affected by dietary patterns and nutritional status of the patients. India being a large country, diet patterns vary from one state to another. Thus, we suspect a close association between dietary intake and alterations in homeostasis of calcium and phosphorus in CKD patients. Therefore, we conduct this study to describe the effect of dietary factors and nutritional status on serum calcium and phosphorus levels in CKD patients on treatment in a tertiary care setting in North India.
Methods: In the present study 330 CKD patients coming to dialysis unit, were recorded with detailed Medical history as well as baseline demographic data. Also, biochemical analysis of serum albumin corrected, calcium, phosphorus, and serum albumin of all cases were done using fully automated equipment. All statistical analyses were performed using SPSS statistical software.
Results: Majority (58.2 %) of the study patients were vegetarians with a mean value of BMI (Mean±SD=23.75±4.70 kg/m2). A negative but significant correlation was found between corrected calcium and phosphorus with 0.05 level of confidence interval (r=-0.149, p= 0.007).
Conclusion: It was found that the well-nourished patients were more likely to be hyperphosphatemic as compared to poorly nourished patients, but statistically the values were found to be nonsignificant (Statistically p-value was not less than 0.05).
Peer Review History:
Received 27 December 2019; Revised 9 January; Accepted 12 January, Available online 15 January 2020
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Average Peer review marks at initial stage: 6.5/10
Average Peer review marks at publication stage: 8.5/10
Name: Dina Abd Elfattah Eldakhs
Affiliation: Pharos university (PUA), Egypt
Name: Dr. Mohammad Tauseef
Affiliation: Department of Pharmaceutical Sciences College of Pharmacy, Chicago State University
Comments of reviewer(s):