PREVALENCE OF STAPHYLOCOCCUS AUREUS IN DENTAL INFECTIONS AND THE OCCURRENCE OF MRSA IN ISOLATES

  • Ameen Abdullah Yahya Al-Akwa Orthodontics, Pedodontics and Prevention Department Faculty of Dentistry, Sana'a University, Yemen
  • Abdul Qader Mohammed Qasem Zabara Orthodontics, Pedodontics and Prevention Department Faculty of Dentistry, Sana'a University, Yemen
  • Hassan Abdulwahab Al-Shamahy Departement of Basic Sciences, Faculty of Dentistry, Sana’a University, Republic of Yemen https://orcid.org/0000-0001-6958-7012
  • Mohammed A Al-labani Orthodontics, Pedodontics and Prevention Department Faculty of Dentistry, Sana'a University, Yemen
  • Khaled M Al-Ghaffari Department of Conservative Dentistry and Oral Health, Sana’a University, Republic of Yemen
  • Ammar M Al-Mortada Department of Maxillo-Facial, Faculty of Dentistry, Sana’a University, Republic of Yemen
  • Ahmed M. Al-Haddad Department of Medical Laboratories, College of Medicine and Health Sciences, Hadhramout University, Al-Mukalla, Yemen
  • Amani Abdulhakeem Al-Sharani Oral Medicine and Periodontology Department, College of Dentistry, University of Sciences and Technology, Yemen

Abstract

Objectives:  Staphylococcus aureus is an opportunist that causes systemic infections and dental infections in the human being body. This organism increases its resistance to many categories of antibiotics all day and turn out to be more resistant, and this led to a growing feeling of concern in this era. Given this fact, the aims of this study were to determine the frequency of S. aureus in oral infections and to determine the prevalence of MRSA strains and the sensitivity of isolated S. aureus to antibiotics, in patients who attended dental clinics in major public hospitals and private clinics in the city of Sana'a-Yemen.


Subjects and methods:  The study was conducted for a year, early in December 2018 and ending in November 2019. The study included 296 patients, 153 male and 143 female, ages 5 to 65, with an average age of 36.2 years. Demographic and clinical data were collected in questionnaire, then pus or oral swabs were collected from patients, cultivated, isolated and identified by standard laboratory techniques. MRSA was ascertained by means of the method of disc diffusion to 1µg of oxicillin disc and 5 µg of methacillin disc; an antimicrobial sensitivity test was carried out by disc diffusion method of selected antibiotics.The oral  infections include  dental abscesses,  periodontal abscesses, gingivitis, periodentitis, dental caries,  pulpitis and oral thrush.


Results:  Of a total of 296 cultured pus and swabs, only 217 produced a positive culture (73.3%). Gram-positive bacteria formed 67.4% of the total isolates where S. aureus was the predominant pathogen (43.1%).  The prevalence of MRSA was 23.5%. There was a higher rate of antibiotic resistance tested in MRSA isolates compared to a lower rate of resistance in MSSA as well as 22.2% of MRSA isolates were vancomycin resistant, while only 11.4% of MSSA were vancomycin resistant.


Conclusion:  It can be concluded, S. aureus was the most widespread isolate in dental infections, high rate of  MRSA,  the appearance of S. aureus isolates resistant to vancomycin and other broad choice of antibiotics have raised MRSA in oral infections into a multi-drug-resistant, making it more and more hazardous in oral infections. Consistent assessment of oral associated infections and observing the pattern of antibiotic sensitivity and strict drug policy for antibiotics are recommended.


Peer Review History:


Received 16 April 2019; Revised 2 May; Accepted 12 May, Available online 15 May 2020


UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.


Received file


pdf3.JPG


Average Peer review marks at initial stage: 5.5/10


Average Peer review marks at publication stage: 8.0/10


Reviewer(s) detail:


Name: Dr. Mohamed Awad Mousnad


Affiliation: Faculty of Pharmacy, International University of Africa (IUA), Khartoum, Sudan


E-mail: m_abdalaziz@yahoo.com


 


Name: Dr. George Zhu 


Affiliation: Tehran University of Medical Sciences, Tehran, Iran


E-mail: sansan4240732@163.com


Comments of reviewer(s):


word_icon_3.jpg


Similar Articles:


PREVALENCE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AND ANTIMICROBIAL SUSCEPTIBILITY PATTERNS AT A PRIVATE HOSPITAL IN SANA'A, YEMEN


PREVALENCE, ANTIMICROBIAL SUSCEPTIBILITY PATTERN AND RISK FACTORS OF MRSA ISOLATED FROM CLINICAL SPECIMENS AMONG MILITARY PATIENTS AT 48 MEDICAL COMPOUND IN SANA'A CITY-YEMEN

Keywords: Antibiotic resistance, dental infection, MRSA, Staphylococcus aureus, Sana'a, Yemen
Statistics
51 Views | 51 Downloads
How to Cite
Al-Akwa, A. A. Y., A. Q. M. Q. Zabara, H. A. Al-Shamahy, M. A. Al-labani, K. M. Al-Ghaffari, A. M. Al-Mortada, A. M. Al-Haddad, and A. A. Al-Sharani. “PREVALENCE OF STAPHYLOCOCCUS AUREUS IN DENTAL INFECTIONS AND THE OCCURRENCE OF MRSA IN ISOLATES”. Universal Journal of Pharmaceutical Research, Vol. 5, no. 2, May 2020, doi:https://doi.org/10.22270/ujpr.v5i2.384.
Section
Research Articles

Most read articles by the same author(s)