A STUDY OF PHYTOCHEMICAL CONSTITUENTS IN CARALLUMA QUADRANGULA
Objectives: Caralluma belongs to the family Asclepiadaceae, native to the Indian sub-continent have different medicinal properties and used in folk medicine as remedies to treat wide variety of diseases and health conditions.
Objective of present study was to isolate, analyze and identify the phytochemicals composition from steam of Caralluma quadrangula.
Methods: Extractions of the chemical components was carried out by different chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry.
Results: The quantitative phytochemical analysis of this species exhibited the presence of three compounds, Glochidonol (5gm), Dihydroxy-14-pregn-5-en-20-one (9.8gm), Hydroxystigmast-5-en-7-one (7.8gm) and Stigmasterol (5.7 mg). Hydroxystigmast-5-en-7-one, report from Caralluma quadrangula stem as first time.
Conclusion: The present study is strengthen for the discovery three pure chemical compounds from C. quadrangula.
Peer Review History:
Received 2 April 2019; Revised 22 April; Accepted 7 May, Available online 15 May 2020
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Average Peer review marks at initial stage: 4.5/10
Average Peer review marks at publication stage: 7.0/10
Name: Ahmad Najib
Affiliation: Universitas Muslim Indonesia, Makassar, Indonesia
Name: Dr. Hatem Sameir Abbas
Affiliation: Al-Azhar University, Egypt
Comments of reviewer(s):