A STUDY OF PHYTOCHEMICAL CONSTITUENTS IN CARALLUMA QUADRANGULA

Abstract

Objectives:  Caralluma belongs to the family Asclepiadaceae, native to the Indian sub-continent have different medicinal properties and used in folk medicine as remedies to treat wide variety of diseases and health conditions.


Objective of present study was to isolate, analyze and identify the phytochemicals composition from steam of Caralluma  quadrangula.


Methods:  Extractions of the chemical components was carried out by different chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry.


Results:  The quantitative phytochemical analysis of this species exhibited the presence of three compounds, Glochidonol (5gm), Dihydroxy-14-pregn-5-en-20-one (9.8gm), Hydroxystigmast-5-en-7-one (7.8gm) and Stigmasterol (5.7 mg). Hydroxystigmast-5-en-7-one, report from Caralluma  quadrangula stem as first time.    


Conclusion:  The present study is strengthen for the discovery three pure chemical compounds from C. quadrangula.


Peer Review History:


Received 2 April 2019; Revised 22 April; Accepted 7 May, Available online 15 May 2020


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Received file


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Average Peer review marks at initial stage: 4.5/10


Average Peer review marks at publication stage: 7.0/10


Reviewer(s) detail:


Name: Ahmad Najib


Affiliation: Universitas Muslim Indonesia, Makassar, Indonesia


E-mail: ahmad.najib@umi.ac.id


 


Name: Dr. Hatem Sameir Abbas


Affiliation: Al-Azhar University, Egypt


E-mail: hsam8406@yahoo.com


Comments of reviewer(s):


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Keywords: Caralluma quadrangula, Glochidonol, 3,14-dihydroxy-14-pregn-5-en-20-one, 3-Hydroxystigmast-5-en-7-one, Stigmasterol
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How to Cite
Al-Mahweety, J. A. N., S. H. Azzam, and A. Alyahawi. “A STUDY OF PHYTOCHEMICAL CONSTITUENTS IN CARALLUMA QUADRANGULA”. Universal Journal of Pharmaceutical Research, Vol. 5, no. 2, May 2020, doi:https://doi.org/10.22270/ujpr.v5i2.385.
Section
Research Articles