SEROPREVALENCE OF DENGUE FEVER VIRUS AMONG SUSPECTED PATIENTS IN TAIZ GOVERNORATE-YEMEN

Qais Yusuf Abdullah; Mohammed Farhan Al-Helali; Anes Al-Mahbashi; Sameh Taha Qaaed; Wadhah Hassan Edrees

doi:10.22270/ujpr.v5i5.482

Qais Yusuf Abdullah Biology Department, Microbiology Section, Faculty of Science, Sana’a University, Yemen.
Mohammed Farhan Al-Helali Biology Department, Microbiology Section, Faculty of Science, Sana’a University, Yemen.
Anes Al-Mahbashi Biology Department, Microbiology Section, Faculty of Science, Sana’a University, Yemen.
Sameh Taha Qaaed Biology Department, Microbiology Section, Faculty of Science, Sana’a University, Yemen.
Wadhah Hassan Edrees Medical Laboratory Department, Faculty of Medical Sciences, Al-Razi University, Yemen. Medical Microbiology Department, Faculty of Applied Sciences, Hajjah University, Yemen.

10.22270/ujpr.v5i5.482

Keywords:

Dengue fever virus, IgG, IgM, Seroprevalence, Taiz governorate, Yemen

Abstract

Background: Dengue Fever virus (DENV) considers one of the most important mosquito-borne viral diseases in the world and it is endemic in more than 100 countries.

Objective: This study aimed to determine the seroprevalence of DENV infection among suspected patients and to investigate some associated risk factors with dengue fever infection in Taiz governorate, Yemen.

Methods: This study was cross-sectional, descriptive, and experimental, combining the use of a structured questionnaire and analysis of serum samples obtained from 300 suspected patients attending at many hospital and clinic centers in Taiz during the period from July to November 2016. The serum samples were tested for anti-dengue immunoglobulin (IgM) and (IgG) by Enzyme-linked Immunosorbent Assay (ELIZA).

Results: Out of 300 suspected febrile cases, it was found that 49(16.3%), 68(22.7%), and 17(5.7%) cases were showed positive for the IgM, IgG, and both IgM and IgG antibodies, respectively, while 166 (55.3%) cases were negative. The incidence rate was more in males than in females. The most affected age group with dengue fever infection were (21–30) years. Dengue Fever was more frequent among patients coming from the urban area, having secondary school, and low-income status people. Also, there was statistical significant between DENV infections with a place of residencyand gender (P<0.05) and not-statistical significance between DENV infections and other factors (P>0.05).

Conclusion: Taiz governorate become one of the endemic governorates in Yemen particularly the Taiz city which should be brought to the attention of public health authorities.