FAST DISSOLVING TABLETS: A PROMISING APPROACH FOR DRUG DELIVERY

  • Vaishali Chauhan Global Institute of Pharmaceutical Education and Research, Kashipur, Uttarakhand, India
  • Kapil Kumar Global Institute of Pharmaceutical Education and Research, Kashipur, Uttarakhand, India
  • Deepak Teotia Global Institute of Pharmaceutical Education and Research, Kashipur, Uttarakhand, India

Abstract

Aim of novel drug delivery system is to enhance safety and efficacy of drug molecules by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach led to development of fast dissolving tablets. Now-a-days fast disintegrating tablets (FDTs) gaining significance with wide variety of drugs serving many purposes. These are novel types of tablets that disintegrate/dissolve/ disperse in saliva within few seconds (less than 60 seconds) without chewing and additional water. The basic approach used in development of FDTs is the use of superdisintegrants and the elimination of bitterness. FDTs reduces the disadvantages of conventional dosage form especially dysphasia (difficulty in swallowing) in pediatric and geriatric patients. These oral dosage forms have many benefits such as self medication, increased compliance, ease of manufacturing and noninvasive. This review presents description of fast dissolving tablets including need for development, challenges in formulation, suitability of drug candidates, composition, various technologies involved, advantages, disadvantages, and evaluation parameters.


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Keywords: Fast dissolving tablet, superdisintegrants, disintegration
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How to Cite
Chauhan, V., K. Kumar, and D. Teotia. “FAST DISSOLVING TABLETS: A PROMISING APPROACH FOR DRUG DELIVERY”. Universal Journal of Pharmaceutical Research, Vol. 2, no. 4, July 2017, doi:https://doi.org/10.22270/ujpr.v2i4.RW4.
Section
Review Articles